Mild Cognitive Impairment in Alzheimer‘s Disease: Two Case Histories

Authors

  • Archibaldo Donoso S. Departamento de Psicología, Facultad de Ciencias Sociales, Universidad de Chile
  • Carolina Vásquez V.

Abstract

Two senior patients, who consulted on account of their recent memory losses are
presented. Both patients fulfilled the criteria of mild cognitive impairment. The first
was followed during a period of five years, and only in the last interview an early
onset of Alzheimer’s disease was suspected. The second presented a more accelerated course and was clinically diagnosed as an Alzheimer’s type dementia two years after the first evaluation.
Mild cognitive impairment is an entity in which case boundaries are not yet clearly
established, but appears as an intermediate stage between normal aging and dementia. 
It makes possible a diagnosis or suspicion of Alzheimer’s disease without dementia. Serial psychometric evaluations and necropsy of aging people may disclose that there exists a preclinical Alzheimer’s disease in subjects without cognitive deterioration.
Quality of life style is among the factors of risk which enables the prediction of dementia in old age, so that it is possible to learn how to minimize the risks of becoming demented.

Keywords:

Aging, mild cognitive impairment, Alzheimer’s disease.